Doing so will cause it to increase in size, and also increase their damage and the damage of the burst tears, Once a tear is fed 5 times, it will immediately burst, Tears in the burst will deal half the damage the main tear would have, Added as part of the Afterbirth+ Booster Pack #4. Defeating Mega Satan as one of the B-side characters unlocks a whole new object a la Lucky Pennies. Killing a petrified enemy will freeze it. 13 Holy Mantle. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. Repentance added many new items into the Secret Room that basically instantly win you the run such as the Red Key, Rock Bottom (Boss Rush as Jacob and Esau), and Echo Chamber (The Beast as Tainted Apollyon). The priority list of what will drop from champion enemies in order is as follows: Soul Hearts - When you have no red heart containers and less than 2 soul hearts, Red Hearts (Full hearts) - While at 0.5 red hearts, Red Hearts (Full hearts) - When you have at least half a red heart container empty, Trinkets - If you have no trinkets and there are no trinkets on the ground in the room, Soul Hearts - When you have less than 6 total heart containers of any kind, If none of the above conditions are true, champions will resume dropping their regular pickups, UNLOCK: Unlock this item by defeating Greedier mode with Maggy, Allows you to fire tears diagonally by holding down two of the fire buttons at once, If you are using a gamepad, this item allows you to fire in any direction, The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode, If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go, Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. Curse Rooms and Blood Donation Machines don't trigger this effect, Items with a price will spawn the extra item free of charge (i.e. Each use of this item gives +0.7 Damage Up, -0.18 Speed Down and the ability to destroy most obstacles for the current room. UNLOCK: Unlock this card by beating Challenge #9 (Demo Man), Temporarily makes Isaac huge, giving him +7 Damage Up and +30 Range Up for the rest of the current room, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140, UNLOCK: Unlock this item by getting 5 items or consumables that increase your size, e.g. 14 Psy Fly. How do you unlock Godhead? UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith, Item Pool: Item Room, Red Chest, Curse Room, During the transition between floors, this item shows you a preview of the item that will spawn in the item room, and the boss that will appear, This effect will work even if you have Curse of the Blind, but the item will still appear as a ? UNLOCK: Unlock this item by defeating Mother in the Corpse II as ??? The Crane Game pool has really good items on average, with items like Tech X, Cricket's Head, Small Rock, the D6, and many more. pants, under wear, pink, knickers, moms underwear, mom underwear, REPENTANCE - Touching enemies deals 12 damage to them, Item Pool: Boss Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels, Drops a random heart on the floor when picked up, * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray, UNLOCK: Unlock this item by beating Mom's Heart 4 times, Gives Isaac angel wings for the current room, allowing him to fly, Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights, If used during the Satan fight, The Bible will instantly kill Isaac, Counts as 1 of 3 angel items needed towards the Seraphim transformation, REPENTANCE - Reduced to 4 room recharge time, * library pool, library room, book room pool, angel room pool, god room pool, angel room item, are both top tier unlocks! blue, glow, 69, Isaac increases in size, gets a lion's mane and now has the ability to crush rocks by walking over them, Crushed rocks and poop can fill holes if you walk in their direction, Allows you to crush Red Poops and sometimes not take damage. Counts as 1 of 3 fly items needed towards the Beelzebub transformation. * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, . Tears now have a chance to cause enemies to be magnetized, Magnetized enemies attract other enemies, tears (including Isaac's) and enemy projectiles, causing them to be pulled in towards them, Enemy tears that get pulled into other enemies will hurt them, You have a chance to fire a tear that marks enemies red and slow them, Marked enemies will be attacked by other enemies either until it is killed or it kills all the other enemies attacking it, Chance to fire a marking tear scales with your luck stat, This item has a different effect for each character. He won't respawn even if you move to a new floor, Will always match your current movement speed, UNLOCK: Unlock this item by defeating The Beast as Tainted Keeper, Only found in the Mausoleum/Gehenna II boss room, The item itself has no effect, but triggers the ascent through the backwards path towards the Home floor. Donation machines become fixed if they were jammed before using the R Key, Isaac now has a chance to fire a fist instead of normal tears, which have a much higher knockback effect and confuse enemies for a few seconds, Enemies that are knocked back will take 10 damage and knock back any enemy they are knocked into, dealing damage to them as well, An active item that allows you to throw an eraser at any enemy, which will kill it and prevent it from appearing for the rest of the run, Enemies that are erased create a puff of smoke instead of spawning, Works on bosses, except it doesn't kill them it just deals 15 damage, Can only be used once per floor - batteries also cannot be used to recharge it to bypass this restriction, The first use will raise it above your head, then by pressing the fire button it will be thrown in that direction, Recharge time: 1 room (Can only be used once per floor), When used, this item will give you +1 Rotten Heart, Rotten Hearts act as red hearts and each one you currently have spawns 2 blue flies upon successfully clearing a room, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Maggy, Enemies now create a soul upon death, which is automatically sucked into the Urn giving it +1 charge. Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. Also, it was free win because i got Polyphemus on it (I think there's an issue with the Armor scaling on her which is why this causes the crash. At the full 12 charges Isaac does a massive shout, dealing 356 damage to all enemies on the screen, Larynx gains 1 charge every time you take damage (also charges as normal), UNLOCK: Unlock this item by defeating The Beast as Tainted Samson, Recharge time: 12 rooms (Can be used with partial charges), This item gives you a familiar version of The Lost character which dies instantly upon hit, If the familiar survives an entire floor you get one of: 3 soul hearts, 2 eternal hearts or a random item/angel room item, Regenerates at the start of each floor if dead, UNLOCK: Unlock this item by defeating Mother in the Corpse II as The Lost, Bombs now spawn a puddle of red creep upon explosion, dealing 2 damage per tick to enemies touching it, While at 0 bombs, you can also place further bombs now at the cost of 1/2 of a heart (kills The Lost if used like this). Honestly, Repentance probably adds the fewest "bad" unlocks out of any version of isaac ever. It can spawn familiars you haven't unlocked yet! Eden I find very fun as well due to his randomness. You just need to complete the Lost's post-it on Hard to unlock Godhead. Counts as 1 of 3 book items needed towards the Bookworm transformation. Type: Passive. Increases the time that status effects stay on enemies. when entering the item room, Gives +1 Soul Heart when starting each new floor after picking this up, Currently this effect doesn't work in Greed Mode - It will show 2 items but the item rooms will have different items in them, Gives +0.4 Tears Up for each room completed without taking damage, up to a maximum of +2.0 Tears Up, When you take damage, the tears bonus is reset, Picking this item up counts and gives you a temporary +0.4 Tears Up as well, Allows you to double-tap the shoot button to create a holy shield for 1 second that pushes enemies back and deals 10 damage to them if they touch it, The shield also reflects enemy shots and beams back at them for some extra damage, Can only be activated every 3 seconds (Shown by a white glow and a ticking noise). Toxic Dips release a poison cloud when they move/die. ?? The item grants Isaac a fly follower that protects him from all enemy bullets, and it does that job almost too well. Tears are now white, do a lot more damage and move slower across the screen with a homing effect, * angel room pool, god room pool, angel room item, red, fire, flame, orange, cross, Does not increase your damage, simply makes your tears red, * boss room pool, boss room item, sticks, brown, yellow, * angel room pool, god room pool, angel room item, the lost item pool, cup, wooden, gold, with Brimstone it fires 10 lasers), Turns your tears into bones, which shatter into 1-3 smaller bone shards upon hitting any object or enemy, The smaller bone shards deal damage equal to half your normal tear damage, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lazarus, Allows Isaac to carry two cards, runes or pills (or any combination of these) at the same time, Drops a random card, pill or rune on pickup, UNLOCK: Unlock this item by beating Greedier Mode with The Lost, Item Pool: Boss Room, Beggar, Gold/Stone Chest, *, silver, metal, grey, gray, omega, dads lost coin, dad lost coin, dad coin, REPENTANCE - This was renamed from Moldy Bread, *, sandwich, toast, brown, green, bite, bitten, Each time you take damage from any source, Cone Head has a 20% chance to prevent it from reducing your health, Isaac flashes blue very briefly when damage is negated by this item, * northernlion, nl, northern lion, ryan letourneau, egg, egg father, egg daddy, dad, BALD, northernlion's head resembles an egg much like this item, isn't that hilarious?, pink, Isaac's tears have a 20% chance to be a booger instead, which stick on to enemies and deal periodic poison damage until they die, Each tick of poison damage is equal to your normal tear damage, Each booger persists for 10 seconds or until the enemy dies. This spawns friendly charger enemies and causes Isaac to deal 5 contact damage (same as the shade did). Heart - 26.6% chance, Trinket - 6.6% chance. ?, Satan and The Lamb as Tainted Eden, Each brand new room, this trinket has a chance to transform into a copy of a random passive item, which gives you the effect for the duration of this room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eden, Gives a small chance to spawn a friendly Bony when clearing a room, which will throw bones at enemies until it takes enough damage to die, Can be either the regular white Bony or the black variant, UNLOCK: Unlock this trinket by defeating Isaac, ?? Doing this will cause this Golden Battery to reappear somewhere else on the floor, UNLOCK: Unlock this by defeating Mega Satan as Tainted Forgotten, Spawns similar to regular troll bombs and cannot be picked up, However, they will explode forever instead of disappearing, The Safety Scissors trinket will turn this into a gold bomb, When picked up, will respawn again at a random location in the room, Every time you pick up a golden penny it has a 5% chance to disappear completely, UNLOCK: Unlock this by defeating Mega Satan as Tainted Keeper, Once picked up, the gold heart will drop money on the floor the next time Isaac loses a heart, UNLOCK: Unlock this item by beating challenge #21 (XXXXXXXXL), Takes three hits to deplete and can be refilled with red hearts, but disappears forever when depleted, UNLOCK: Unlock this item by unlocking the Forgotten character. Pool, gold chest pool, item room, item room, item room, room! 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