Another important counterpoint to Dr. Bossches claim is that we can simply reformulate our vaccines to match new variants of concern. He is at present primarily serving as a Biotech / Vaccine consultant while also conducting his own research on Natural Killer cell-based vaccines. Its a rationale for developing reformulated booster vaccines that cover variants not well covered by the currently-used COVID-19 vaccines. The COVID-19 pandemic has attracted a swarm of vocal contrarians like little else in the recent past. Vaccines make use of the adaptive part of our immune system. I'm glad I finally know. Mass vaccination during pandemic historical blunder: Nobel laureate The technology enables the development of universal vaccines educating the host immune system to redirect immune targeting away from canonical antigens to a widely divergent spectrum of vitally vulnerable pathogen-derived self-mimicking antigens, irrespective of MHC polymorphism. Variants are "a thing to keep an eye on," Saad Omer, an epidemiologist who serves as director of the Yale Institute for Global Health, told us in a phone interview. Compre online The Inescapable Immune Escape Pandemic, de Vanden Bossche MD Phd, Geert na Amazon. A Belgian virus expert has scared the Internet by claiming the COVID-19 vaccines will doom humanity. There is a reason why a new flu vaccine is made each year: the influenza virus drifts and shifts and the vaccine needs to be reformulated to be a better match for the specific viruses that are predicted to be common during the next flu season. Vaccine Expert Vanden Bossch Believes Mass Vaccination Is Likely To Turn The Relatively Harmless Virus Into A Bioweapon (drug, retired) . The production of targeted antibodies obviously creates a different response than a natural infection because "you're producing antibodies against specific needs therefore you have a limited targeted immune response, not the whole response that you see after an infection." In any case, I got a particularly strong brave maverick vibe from this passage: While there is no time to spare, I have not received any feedback thus far. So the question becomes: do the COVID-19 vaccines give us low or high levels of neutralizing antibodies? Dr. Vanden Bossche received his DVM from the University of Ghent, Belgium, and his PhD degree in Virology from the University of Hohenheim, Germany. Geert Vanden Bossche on LinkedIn: The Inescapable Immune Escape The classic example of a leaky vaccine is actually the one for Mareks disease, caused by a herpesvirus that infects chicken and causes lymphoma among other illnesses. Thankfully, there is a vaccine against it, but over time, newer and more virulent strains of the virus have been detected, and this made scientists think it was because the vaccine was leaky, that it did not allow the chicken to mount a good enough immune response. Basically, Dr. Vanden Bossches open letter is a mess that directly channels Andrew Wakefield. The role of the innate immune response in COVID-19 infections is not fully understood. This innate immunity gambit on the part of Dr. Bossche is something typically seen in wellness communities obsessed with the naturalistic fallacy, where strengthening your immune system is as simple and as natural as taking in the sun, walking in the woods, and hugging people. Geert Vanden Bossche The Inescapable Immune Escape Pandemic Hardcover - June 8, 2023 by Geert Vanden Bossche MD PhD (Author) 15 ratings See all formats and editions Kindle $19.99 Read with Our Free App Hardcover $49.99 1 New from $49.99 Pre-order Price Guarantee. As the virus spreads, it mutates here and there and new variants of concern emerge. We are sorry. Enhanced typesetting improvements offer faster reading with less eye strain and beautiful page layouts, even at larger font sizes. Thus if evidence emerges that particular variants do appear to influence vaccine efficacy, it should be possible to periodically reformulate the vaccines so that they better match the circulating strains. Moreover, as Nirenberg points out, there is an increasing body of evidence that the COVID-19 vaccine is not leaky. Dr Geert Vanden Bossche from Belgium - what's the truth? The Inescapable Immune Escape Pandemic by Geert Vanden Bossche Although non-self and exposed on the surface of infected or pathologically altered cells, these antigens are not effectively recognised upon natural infection or disease. The Inescapable Immune Escape Pandemic : Vanden Bossche MD Phd, Geert See | 71 comments on LinkedIn He held adjunct faculty appointments at universities in Belgium and Germany. Even if they dont prevent all transmissions, it looks like they can drastically cut the transmission chain and also reduce the amount of virus that can be transmitted in these cases. Mass vaccination programs, he claims, are "turning vaccinees into asymptomatic carriers" who can unknowingly spread these more dangerous strains by "shedding infectious variants." pandemic is now at risk of resultng in a global catastrophe without equal, this call cannot sound loudly . Even so, concern about immune escape is one reason why Pfizer, BioNTech, and Moderna used the entire SARS-CoV-2 spike protein, rather than specific segments of it that might serve as antigens, so that the polyclonal antibody immune response generated would be broad and unlikely to be escaped with single mutationsor even multiple mutations. But if you have a full and overpowering army at your command, the invaders wont stick around for long. Word Wise helps you read harder books by explaining the most challenging words in the book. The author delves into the impact of mass vaccination on individual and global health, and explains how powerful organizations, institutions, and industries lacking an understanding of this complex environment have turned a natural viral pandemic into one of disastrous immune escape. Geert then moved on to join the Bill & Melinda Gates Foundations Global health discovery team in seattle (USA) as senior Program officer. https://www. Select your subscriptions from a range of popular titles and find the latest issue in your library. Highlighting the principle of using a prophylactic vaccine in the midst of a pandemic. Snopes and the Snopes.com logo are registered service marks of Snopes.com, Image Via Screencapture / geertvandenbossche.org. ON NOVEMBER 27, 2021, 7:30pm, Philippine Time, Professor Geert Vanden Bossche will be the guest speaker on the topic of "The Implications of Mass Vaccination During the Pandemic." Register now and reserve your seats. MASS VACCINATION of the ELDERLY. (I note that Dr. Vanden Bossche only set up his Twitter account two weeks ago and already has over 16K followers.) One such claim that I hadnt yet seen is another favorite antivax claim, although admittedly its a rather niche claim in that you dont hear it too often. So, as we grow up, we increasingly mount pathogen-specific immunity, including highly specific Abs. PDF Geert Bossche: Halt All Covid-19 Mass Vaccination (Open Letter to WHO Since 2014, however, he has been trying (apparently unsuccessfully) to develop his so-called universal vaccine. This is due to disruptions in the delivery and uptake of immunization services caused by the COVID-19 pandemic. Its another step in the decades-long erasure of the fact that our sophisticated and highly effective immune systems work well and dont need any assistance from the biomedical/pharmaceutical industry. So, why then should there be a major concern using these vaccines to fight Covid-19? Specifically, scientists have long been pointing out that, the more we let COVID-19 circulate, the more likely virus variants that can escape the immune response to the vaccine (and/or to natural infection) are to emerge, and they use this argument as a rationale for vaccinating as many people as possible as fast as possible, in order to slow that circulation of the virus to as low a rate as possible, thus reducing the opportunities for strains resistant to the vaccine and strains able to re-infect previously infected people to emerge. At birth, our innate immune system is unexperienced but well-established. "There is a sound scientific rationale to assume," Vanden Bossche wrote, "that it is possible to prime NK cells" in ways for them to recognize and kill Coronaviruses at large (including all their variants) at an early stage of infection." Its been accompanied by a video interview posted towhere else?antivaxxer Robert F. Kennedy, Jr.s Childrens Health Defense website. Enjoy! Reading the letter, what it reminded me, more than anything else, is an article that Andrew Wakefield wrote about the MMR vaccine and measles, published a few months before the pandemic hit. 1996-2023, Amazon.com, Inc. or its affiliates, The Kindle title is not currently available for purchase. To use an analogy, if a gaggle of invaders is coming but you have only managed to round up a few soldiers, be prepared for a long siege during which the enemy might learn a thing or two about your defences and adapt. In scenario #1, you get rid of vaccines and lockdowns and allow the virus to spread, practically unimpeded, through the population, killing more and more people and leaving many with long-term health consequences. In online biographies, Vanden Bossche describes himself as "inventor on a patent application for universal vaccines." National Center for Complementary and Integrative Health, Steven P. Novella, MD Founder and Executive Editor, David H. Gorski, MD, PhD Managing Editor, allowing infection and natural herd immunity to occur is better, American Association of Physicians and Surgeons, The Sixth Extinction: Vaccine Immunity and Measles Mutants in a Virgin Soil, excellent rebuttal of Dr. Vanden Bossches mangling of immunology, proofreading mechanism that results in a low mutation rate, Andrew Wakefield wrote about MMR and vaccines, Nirenbergs demolition of Dr. Vanden Bossches nonsense, The Not-So-Hidden Agenda Behind Bossches Concern Over COVID Mass Vaccination, surgical oncologist at the Barbara Ann Karmanos Cancer Institute, American College of Surgeons Committee on Cancer Liaison Physician, Ear Acupuncture for Procedural Pain in Neonates: More Randomized Controlled Nonsense. A study of the Moderna vaccine in 34 participants showed high levels of binding and neutralizing antibodies that declined slightly over time, as expected, but [that] remained elevated in all participants three months after the booster vaccination. More broadly, data from the vaccine clinical trials and from countries that have vaccinated a large percentage of their population show a significant reduction in cases and mortality. This is an absurdly counterproductive solution if Vanden Bossche were truly concerned about variants. NK cells are part of the cellular arm of our innate immune system and, alike [sic] natural Abs, they are capable of recognizing and attacking a broad and diversified spectrum of pathogenic agents. FDA: Vaccines Don't Have To Prevent Infection Or Transmission As the unprecedented extent of human intervention in the Covid-19- pandemic is now at risk of resulting in a global catastrophe without equal, this call cannot sound loudly and strongly enough. This strategy is based on vaccines that target the adaptive arm of our immune system, the same principle that allowed us to slay smallpox and bring polio and measles down to their knees. As those have stronger affinity for the pathogen (e.g., virus) and can reach high concentrations, they can quite easily outcompete our natural Abs for binding to the pathogen/virus. While one can barely make any incorrect scientific statements without being criticized by peers, it seems like the elite of scientists who are currently advising our world leaders prefer to stay silent. Statement by Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, formerly employed at GAVI and The Bill & Melinda Gates Foundaton. If you are ready to for the truth, this book will be painful but finally make sense After three years of hearing all kinds of explanations and mixed messaging, this book finally brings clarity to what's been going on. As I noted when Andrew Wakefield explicitly used the example of Mareks disease to claim that a leaky vaccine to MMR would cause a global catastrophe by selecting for deadly measles variants, yes, a leaky vaccine changes the selective pressure and permits the evolution of highly virulent strains because the virus retains the ability to continue to spread among vaccinated populations, leading to the vaccine selecting for the most virulent mutations. The present extremely critical situation forces me to spread this emergency call. The estimated length is calculated using the number of page turns on a Kindle, using settings to closely represent a physical book. For example, just before the three-minute mark in the video interview of Vanden Bossche by McMillan, Vanden Bossche indicates hes a long-time vaccine developer. Author of 'From Midnight to Moonlight' - a book about cats and angels. After his career in Academia, Geert joined several vaccine companies (GSK Biologicals, Novartis Vaccines, Solvay . GENEVA/NEW YORK, 15 July 2020 - The World Health Organization and UNICEF warned today of an alarming decline in the number of children receiving life-saving vaccines around the world. Up to this point, at its core and leaving aside minor variations, Dr. Vanden Bossches argument about COVID-19 vaccines and COVID-19 is pretty close to exactly the same argument that Wakefield fallaciously made about MMR and measles. What would you do? Basically, innate immunity is a bit like Dory the amnesiac fish from Finding Nemo. Claims that Belgium has the best fries in the world! Vaccine Expert Vanden Bossch Believes Mass Vaccination Is Likely To He claims that the vaccines will destroy our bodies' ability to use our innate immune system (which produces, among other things, non-specific cells capable of clearing a wide variety of infectious material from the body) to fight off the variants vaccines allegedly could not. This material may not be reproduced without permission. One of his topics is labeled, "Why mass vaccinaton amidst a pandemic creates an irrepressible monster." His work and supportive advice are driven by a relentless passion to translate scientific breakthrough findings into competitive solutions to emerging challenges in public and global health. The more extensively the later age group will be vaccinated and hence, protected, the more the virus is forced to . you get antibodies that are no longer able to completely neutralize the virus -we are seeing more and more that mass vaccinations can lead to resistance . The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species. FALSE: Geert Vanden Bossche says mass vaccination might boost - Poynter Originally Posted by MissTerri Geert Vanden Bosch didn't use Del Bigtree or JFK jr. to spread his message. A BBC fact check of Vanden Bossche's claim was deemed "false" with multiple vaccine experts saying large scale vaccinations were more likely to weaken the COVID-19 virus, not cause it to mutate to to a morte lethal variant. I am anything but an anti-vaxxer. As previously explained (see contribution: 'Unravelling the complexity of Covid-19 vaccination shaped by mass vaccination'), this beneficial effect will wane quite Natural Abs are not germ-specific whereas acquired Abs are specifically directed at the invading pathogen. Before he gets to his concerns, like anyone spreading antivaccine disinformation, whether as an antivaxxer or someone whos misguided, Dr. Vanden Bossche, like RFK Jr., must proclaim himself so very firmly not antivaccine: I am all but an antivaxxer. This problem will be exacerbated, he claims, because people who have been vaccinated (and/or social distancing and staying inside during the pandemic) will be less capable of fighting off those strains than someone who has not been vaccinated. His work and supportive advice are driven by a relentless passion to translate scientific breakthrough findings into competitive solutions to emerging challenges in public and global health. The author's unique approach and reliance on basic scientific principles make this a valuable addition to the literature on the subject. And lest we forget: the variants of concern making headlines now arose before we had any vaccine against the coronavirus. Dr. Bossches idea that the coronavirus will simply continue moving from person to person and that vaccines will only prevent severe disease is contradicted by the data that is accumulating. PDF Former Gates Vaccine Scientist Predicts Mass Genocide Amazon has encountered an error. Please try again. Cases and deaths go down. Reality aside, invoking the innate immune system provides two rhetorical benefits. For vaccines, resistance equates to strains of the microbe, the virus, or the bacteria that can elude the imperfect immunity created by the vaccine. If you are a potential patient and found this page through a Google search, please check out Dr. Gorski's biographical information, disclaimers regarding his writings, and notice to patients here. Nirenberg goes further and notes that the antibody titers induced by vaccines are MUCH higher than those seen after infection, and we see hallmarks of memory responses induced by these vaccines from even a single dose, suggesting that, even though there is a decrease in neutralization by vaccine-induced SARS-CoV-2 antibodies, that might not portend a loss in protection. His argument sounds a lot like an argument Andrew Wakefield once made for MMR. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. Calculations for herd immunity consider two sources of individual immunity vaccines and natural infection. How long can one ignore the problem when there is at present massive evidence that viral immune escape is now threatening humanity? Exploring issues and controversies in the relationship between science and medicine. He held adjunct faculty appointments at universities in Belgium and Germany. While scientists dont yet know exactly what levels of antibodies are needed to ward off disease, the approved vaccines do elicit the production of neutralizing antibodies. Medical Op-Ed: Mass Vaccination Creates "Excellent Breeding Grounds not enough to swiftly kill the virus when you catch it, this could allow the virus to stick around in your body for a little bit and make copies of itself. The Inescapable Immune Escape Pandemic Hardcover - 8 Jun. 2023 - Amazon Perhaps no more tired a trope exists in the world of faux cures than the "I have found a problem that no other scientist in the world has thought of and only my untested and unproven cure can stop it" gambit. Central to the concept in his article, published via the in-house journal of the American Association of Physicians and Surgeons (AAPS), an organization I like to refer to as the John Birch Society of medical societies given its penchant for conspiracy theories and pseudoscience, was that the MMR vaccine, by selecting for more aggressive measles strains, could result in a sixth extinction event. Today we are in . But even if the COVID-19 vaccines were leaky, meaning they still allowed some vaccinated people to transmit the virus to others, there is evidence that they could still efficiently contain the spread of the disease. The New Jurist | Austria's Mandatory Vaccination Law Unless I am scientifically proven wrong, it is difficult to understand how current human interventions will prevent circulating variants from turning into a wild monster. Maybe. If you are ready to for the truth, this book will be painful but finally make sense out of it all. Imagine you were a public health advisor and were confronted with this choice: to heed Dr. Bossches apocalyptic warning and stop all COVID-19 vaccinations (scenario #1) or to ignore him and follow the evidence (scenario #2). Noting how quickly Dr. Vanden Bossches letter was embraced by antivaxxers, Frei then writes: But from my experience as a former long-time medical writer and journalist (1988-2016) particularly a four-month stint with media-relations giant FleishmanHillard in 1994 (yes, Ive worked for the dark side) this has all the hallmarks of a drug-company astroturf campaign. While Vanden Bossche's ideas may be rooted in actual scientific concepts, his argument quite explicitly relies on sweeping assumptions. geertvandenbossche . This brings us to our topic, a misinformation-filled open letter by a scientist named Geert Vanden Bossche that went viral over the weekend. So, there is not one second left for gears to be switched and to replace the current killer vaccines by life-saving vaccines. After all, if a human vaccine lets deadlier versions of a disease flourish, that is all the more reason to be protected from those deadly strains. SOURCE: Geert Vanden Bossche, Children's Health Defense, The HighWire. Its a common argument among antivaxxers that the reason were seeing more cases of pertussis in people who have been vaccinated against it is because pertussis is either evolving resistance, or because it is shifting to a different strain not covered by the vaccine. The latest example of this phenomenon comes in the form of Dr. Geert Vanden Bossche, who recently published an alarming manifesto. "The underlying fallacy," Omer explained, is that a natural infection is better than a vaccine. A viral open letter by Geert Vanden Bossche has gone viral, and antivaxxers have been citing it as slam-dunk evidence that COVID-19 vaccination will lead to global catastrophe. Bossche explains that as soon as an individual receives their first COVID-19 vaccine, their body will begin to build an immune response, taking weeks to develop fully. Geert Vanden Bossche received his DVM from the University of Ghent, Belgium, and his PhD degree in Virology from the University of Hohenheim, Germany. They shall only be contradicted by science. The Inescapable Immune Escape Pandemic Kindle Edition - Amazon However, as we age, we will increasingly face situations where our innate immunity (often called the first line of immune defense) is not strong enough to halt the pathogen at the portal of entry (mostly mucosal barriers like respiratory or intestinal epithelia). Therefore he has zero credibility when it comes to advising the public or anyone else about how to avoid negative effects of mass vaccination. Five reasons why COVID herd immunity is probably impossible - Nature
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